850200 | Regadenoson
2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine

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Regadenoson
2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine
Regadenoson (Lexiscan) is an A2A adenosine receptor agonist used as a coronary vasodilator in pharmacologic stress testing. Recently, it has been demonstrated that regadenoson can temporarily disrupt the integrity of the blood-brain barrier (BBB) by inhibiting P-glycoprotein function.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Cerqueira MD. The future of pharmacologic stress: selective A2A adenosine receptor agonists. Am J Cardiol. 2004 Jul 22;94(2A):33D-40D; discussion 40D-42D. doi: 10.1016/j.amjcard.2004.04.017. PMID: 15261132.
PubMed ID: 15261132Kim DG, Bynoe MS. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest. 2016 May 2;126(5):1717-33. doi: 10.1172/JCI76207. Epub 2016 Apr 4. PMID: 27043281; PMCID: PMC4855938.
PubMed ID: 27043281- Certificate of Analysis (Lot No. 850200P-5MG-A-010 and 5624PHA010)
- Certificate of Analysis (Lot No. 850200P-5MG-B-010 and 5624PHB010)
- Certificate of Analysis (Lot No. 850200P-5MG-C-010 and 5624PHC010)
- Certificate of Analysis (Lot No. 850200P-5MG-D-010 and 5624PHD010)