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850150 | 18:1 PI(3)P

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-3'-phosphate) (ammonium salt)

18:1 PI(3)P

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Size SKU Packaging Price
100µg 850150P-100ug 850150P-100ug $131.00
500µg 850150P-500ug 850150P-500ug $530.00
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Info

18:1 PI(3)P

1,2-dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-3'-phosphate) (ammonium salt)

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C45H90N2O16P2
Percent Composition
C 55.31%, H 9.28%, N 2.87%, O 26.20%, P 6.34%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246303-09-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
977.147
Exact Mass
976.577
Synonyms
PIP[3'](18:1/18:1)
Downloads
References

Han X, Yang Y, Zhao F, Zhang T, Yu X. An improved protein lipid overlay assay for studying lipid-protein interactions. Plant Methods. 2020 Mar 6;16:33. doi: 10.1186/s13007-020-00578-5. PMID: 32165912; PMCID: PMC7060618.

 PubMed ID: 32165912

Yu CY, Kanehara K. The unfolded protein response modulates a phosphoinositide-binding protein through the IRE1-bZIP60 pathway. Plant Physiol. 2020 Mar 23:pp.01488.2019. doi: 10.1104/pp.19.01488. Epub ahead of print. PMID: 32205450.

 PubMed ID: 32205450

Dai A, Yu L, Wang HW. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nat Commun. 2019 Aug 16;10(1):3699. doi: 10.1038/s41467-019-11694-9.

 PubMed ID: 31420534

Mahajan D, Tie HC, Chen B, Lu L. Dopey1-Mon2 complex binds to dual-lipids and recruits kinesin-1 for membrane trafficking. Nat Commun. 2019 Jul 19;10(1):3218. doi: 10.1038/s41467-019-11056-5.

 PubMed ID: 31324769

Chandra M, Chin YK, Mas C, Feathers JR, Paul B, Datta S, Chen KE, Jia X, Yang Z, Norwood SJ, Mohanty B, Bugarcic A, Teasdale RD, Henne WM, Mobli M, Collins BM. Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nat Commun. 2019 Apr 4;10(1):1528. doi: 10.1038/s41467-019-09355-y.

 PubMed ID: 30948714

Morel E, Chamoun Z, Lasiecka ZM, Chan RB, Williamson RL, Vetanovetz C, Dall'Armi C, Simoes S, Point Du Jour KS, McCabe BD, Small SA, Di Paolo G. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun. 2013;4:2250. doi: 10.1038/ncomms3250.

 PubMed ID: 23907271

Hammond GR1, Fischer MJ, Anderson KE, Holdich J, Koteci A, Balla T, Irvine RF. PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity. Science. 2012 Aug 10;337(6095):727-30. doi: 10.1126/science.1222483. Epub 2012 Jun 21.

 PubMed ID: 22722250

Yokogawa M, Kobashigawa Y, Yoshida N, Ogura K, Harada K, Inagaki F. NMR analyses of the interaction between the FYVE domain of early endosome antigen 1 (EEA1) and phosphoinositide embedded in a lipid bilayer. J Biol Chem. 2012 Oct 12;287(42):34936-45. doi: 10.1074/jbc.M112.398255. Epub 2012 Aug 22.

 PubMed ID: 22915584
Certificates of Analysis

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