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840857 | 16:0-18:1 PA

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)

16:0-18:1 PA

Chloroform

Size SKU Packaging Price
25mg 840857C-25mg 840857C-25mg 1 x 25mg 10mg/mL 2.5mL $97.50
200mg 840857C-200mg 840857C-200mg 2 x 100mg 25mg/mL 4mL $292.00
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Powder

Size SKU Packaging Price
25mg 840857P-25mg 840857P-25mg 1 x 25mg $97.50 97.5
200mg 840857P-200mg 840857P-200mg 2 x 100mg $292.00 292
500mg 840857P-500mg 840857P-500mg 5 x 100mg $525.00 525
Request Bulk Pricing
Info

16:0-18:1 PA

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C37H70O8PNa
Percent Composition
C 63.77%, H 10.12%, Na 3.30%, O 18.37%, P 4.44%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
169437-35-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
696.91
Exact Mass
696.471
Synonyms
1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt)
POPA(16:0/18:1(9Z))
110616
Transition Temp
28°C
Downloads
References

Sun S, Liu C, Rodriguez Melendez D, Yang T, Cremer PS. Immobilization of Phosphatidylinositides Revealed by Bilayer Leaflet Decoupling. J Am Chem Soc. 2020 Jul 20. doi: 10.1021/jacs.0c03800. Epub ahead of print. PMID: 32687699.

 PubMed ID: 32687699

Zhang B, Lewis KM, Abril A, Davydov DR, Vermerris W, Sattler SE, Kang C. Structure and Function of the Cytochrome P450 Monooxygenase, Cinnamate 4-hydroxylase (C4H1) from Sorghum bicolor. Plant Physiol. 2020 Apr 24:pp.00406.2020. doi: 10.1104/pp.20.00406. Epub ahead of print. PMID: 32332088.

 PubMed ID: 32332088

van 't Klooster JS, Cheng TY, Sikkema HR, Jeucken A, Moody B, Poolman B. Periprotein lipidomes of Saccharomyces cerevisiae provide a flexible environment for conformational changes of membrane proteins. Elife. 2020 Apr 17;9:e57003. doi: 10.7554/eLife.57003. PMID: 32301705; PMCID: PMC7182430.

 PubMed ID: 32301705

Tei R, Baskin JM. Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds. J Cell Biol. 2020 Mar 2;219(3):e201907013. doi: 10.1083/jcb.201907013. PMID: 31999306; PMCID: PMC7054994.

 PubMed ID: 31999306

Davydova NY, Dangi B, Maldonado MA, Vavilov NE, Zgoda VG, Davydov DR. Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2. Biochem J. 2019 Dec 12;476(23):3661-3685. doi: 10.1042/BCJ20190532.

 PubMed ID: 31750875

Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion. J Biol Chem. 2019 Sep 12. pii: jbc.RA119.008865. doi: 10.1074/jbc.RA119.008865. [Epub ahead of print]

 PubMed ID: 31515268

Sparks RP, Arango AS, Starr ML, Aboff ZL, Hurst LR, Rivera-Kohr DA, Zhang C, Harden KA, Jenkins JL, Guida WC, Tajkhorshid E, Fratti RA. A small-molecule competitive inhibitor of phosphatidic acid binding by the AAA+ protein NSF/Sec18 blocks the SNARE-priming stage of vacuole fusion. J Biol Chem. 2019 Sep 12. pii: jbc.RA119.008865. doi: 10.1074/jbc.RA119.008865. [Epub ahead of print]

 PubMed ID: 31515268

Patrick JW, Laganowsky A. Probing Heterogeneous Lipid Interactions with Membrane Proteins Using Mass Spectrometry. Methods Mol Biol. 2019;2003:175-190. doi: 10.1007/978-1-4939-9512-7_9.

 PubMed ID: 31218619

Ahlem Eddehech, Nabil Smichi, Yani Arhab, Alexandre Noiriel, Abdelkarim Abousalham, Youssef Gargouri, Zied Zarai. Production, purification and functional characterization of phospholipase C from Bacillus thuringiensis with high catalytic activity. Process Biochemistry. 2019 August;83:122-130. doi: 10.1016/j.procbio.2019.05.012

Heitmeier MR, Hresko RC, Edwards RL, Prinsen MJ, Ilagan MXG, Odom John AR, Hruz PW. Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering. PLoS One. 2019 May 9;14(5):e0216457. doi: 10.1371/journal.pone.0216457. eCollection 2019.

 PubMed ID: 31071153

Reinink P, Souter MNT, Cheng TY, van Gorkom T, Lenz S, Kubler-Kielb J, Strle K, Kremer K, Thijsen SFT, Steere AC, Godfrey DI, Pellicci DG, Moody DB, Van Rhijn I. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells. Eur J Immunol. 2019 Mar 10. doi: 10.1002/eji.201847949. [Epub ahead of print]

 PubMed ID: 30854633

Kim HY, Jin H, Bae J, Choi HK. Metabolic and lipidomic investigation of the antiproliferative effects of coronatine against human melanoma cells. Sci Rep. 2019 Feb 28;9(1):3140. doi: 10.1038/s41598-019-39990-w.

 PubMed ID: 30816283

Amdursky N, Lin Y, Aho N, Groenhof G. Exploring fast proton transfer events associated with lateral proton diffusion on the surface of membranes. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2443-2451. doi: 10.1073/pnas.1812351116. Epub 2019 Jan 24.

 PubMed ID: 30679274

Thomas LL, van der Vegt SA, Fromme JC. A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF. Dev Cell. 2019 Jan 7;48(1):100-114.e9. doi: 10.1016/j.devcel.2018.11.013. Epub 2018 Dec 6.

 PubMed ID: 30528786

Thomas LL, van der Vegt SA, Fromme JC. A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF. Dev Cell. 2019 Jan 7;48(1):100-114.e9. doi: 10.1016/j.devcel.2018.11.013. Epub 2018 Dec 6.

 PubMed ID: 30528786

Cao W, Ma X, Li Z, Zhou X, Ouyang Z. Locating Carbon-Carbon Double Bonds in Unsaturated Phospholipids by Epoxidation Reaction and Tandem Mass Spectrometry. Anal Chem. 2018 Aug 23. doi: 10.1021/acs.analchem.8b02021. [Epub ahead of print]

 PubMed ID: 30095894
Certificates of Analysis

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