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840045 | Brain PI(4)P

L-α-phosphatidylinositol-4-phosphate (Brain, Porcine) (ammonium Salt)

Brain PI(4)P

Powder

Size SKU Packaging Price
1mg 840045P-1mg 840045P-1mg 1 x 1mg $206.18
5mg 840045P-5mg 840045P-5mg 1 x 5mg $738.95
10mg 840045P-10mg 840045P-10mg 1 x 10mg $1,318.40
25mg 840045P-25mg 840045P-25mg 1 x 25mg $2,873.50
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Chloroform/Methanol/Water (20:9:1)

Size SKU Packaging Price
1mg 840045X-1mg 840045X-1mg 1 x 1mg 1mg/mL 1mL $206.18 206.18
5mg 840045X-5mg 840045X-5mg 1 x 5mg 5mg/mL 1mL $738.95 738.95
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Info

Brain PI(4)P

L-α-phosphatidylinositol-4-phosphate (Brain, Porcine) (ammonium Salt)

Data
Hygroscopic
Yes
Light Sensitive
Yes
Purity
>99%
Stability
3 Months
Storage Temperature
-20°C
CAS Number
475995-51-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
974.764
Synonyms
cephalin
Downloads
References

Sun S, Liu C, Rodriguez Melendez D, Yang T, Cremer PS. Immobilization of Phosphatidylinositides Revealed by Bilayer Leaflet Decoupling. J Am Chem Soc. 2020 Jul 20. doi: 10.1021/jacs.0c03800. Epub ahead of print. PMID: 32687699.

 PubMed ID: 32687699

Dai A, Yu L, Wang HW. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nat Commun. 2019 Aug 16;10(1):3699. doi: 10.1038/s41467-019-11694-9.

 PubMed ID: 31420534

Nishimura T, Gecht M, Covino R, Hummer G, Surma MA, Klose C, Arai H, Kono N, Stefan CJ. Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P2 Synthesis. Mol Cell. 2019 Sep 5;75(5):1043-1057.e8. doi: 10.1016/j.molcel.2019.06.037. Epub 2019 Aug 8.

 PubMed ID: 31402097

Mahajan D, Tie HC, Chen B, Lu L. Dopey1-Mon2 complex binds to dual-lipids and recruits kinesin-1 for membrane trafficking. Nat Commun. 2019 Jul 19;10(1):3218. doi: 10.1038/s41467-019-11056-5.

 PubMed ID: 31324769

Rahajeng J, Kuna RS, Makowski SL, Tran TTT, Buschman MD, Li S, Cheng N, Ng MM, Field SJ. Efficient Golgi Forward Trafficking Requires GOLPH3-Driven, PI4P-Dependent Membrane Curvature. Dev Cell. 2019 Jun 7. pii: S1534-5807(19)30451-4. doi: 10.1016/j.devcel.2019.05.038. [Epub ahead of print]

 PubMed ID: 31231041

Jamecna D, Polidori J, Mesmin B, Dezi M, Levy D, Bigay J, Antonny B. An Intrinsically Disordered Region in OSBP Acts as an Entropic Barrier to Control Protein Dynamics and Orientation at Membrane Contact Sites. Dev Cell. 2019 Mar 16. pii: S1534-5807(19)30144-3. doi: 10.1016/j.devcel.2019.02.021. [Epub ahead of print]

 PubMed ID: 30905771

Thomas LL, van der Vegt SA, Fromme JC. A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF. Dev Cell. 2019 Jan 7;48(1):100-114.e9. doi: 10.1016/j.devcel.2018.11.013. Epub 2018 Dec 6.

 PubMed ID: 30528786
Fatty Acid Distribution

This Natural Lipid is a mixture and the structure shown above is only representative of one possible structure present in the product. Refer to chart for average fatty acid distribution.

840045FattyAcidDistribution.gif
Certificates of Analysis

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