810284 | TopFluor™ Lyso PC

1-(dipyrrometheneboron difluoride)undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

TopFluor™ Lyso PC

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Info

TopFluor™ Lyso PC

1-(dipyrrometheneboron difluoride)undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Fluorescent derivative of lyso phosphatidylcholine with spectral properties similar to BODIPY-FL.

Data
Hygroscopic
No
Light Sensitive
Yes
Molecular Formula
C32H53BF2N3O7P
Percent Composition
C 57.23%, H 7.95%, B 1.61%, F 5.66%, N 6.26%, O 16.68%, P 4.61%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer.
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2260795-53-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
671.561
Exact Mass
671.368
Ex/Em
495/503nm
References

Jia Zhou, Xiaojing Chi, Min Cheng, Xingyao Huang, Xiuying Liu, Jingjing Fan, Hua Xu, Tianli Lin, Lei Shi, Chengfeng Qin, Wei Yang. Zika virus degrades the w-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis. Zhou et al., Sci. Adv. 2019; 5 : eaax7142 23 October 2019.


Chagas-Lima AC, Pereira MG, Fampa P, Lima MS, Kluck GEG, Atella GC. Bioactive lipids regulate Trypanosoma cruzi development. Parasitol Res. 2019 Sep;118(9):2609-2619. doi: 10.1007/s00436-019-06331-9. Epub 2019 Jul 2.

PubMed ID: 31267245

Wu D, Jin X, Wang X, Ma B, Lou C, Qu H, Zheng J, Zhang B, Yan X, Wang Y, Jing L. Engineering temperature-sensitive plateletsomes as a tailored chemotherapy platform in combination with HIFU ablation for cancer treatment. Theranostics. 2019 May 31;9(13):3966-3979. doi: 10.7150/thno.32172. eCollection 2019.

PubMed ID: 31281525

Piccirillo AR, Hyzny E1, Beppu LY, Menk AV, Wallace CT, Hawse WF, Buechel HM, Wong BH, Foo JC, Cazenave-Gassiot A, Wenk MR, Delgoffe GM, Watkins SC, Silver DL, D'Cruz LM. The Lysophosphatidylcholine Transporter MFSD2A Is Essential for CD8+ Memory T Cell Maintenance and Secondary Response to Infection. J Immunol. 2019 Jul 1;203(1):117-126. doi: 10.4049/jimmunol.1801585. Epub 2019 May 24.

PubMed ID: 31127034
Certificates of Analysis

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