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810218 | C6-NBD Sphingomyelin

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sphingosine-1-phosphocholine

C6-NBD Sphingomyelin

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1mg 810218P-1mg 810218P-1mg 1 x 1mg $510.29
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Chloroform

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1mg 810218C-1mg 810218C-1mg 1 x 1mg 1mg/mL 1mL $510.29 510.29
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Info

C6-NBD Sphingomyelin

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sphingosine-1-phosphocholine

Data
Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C35H61N6O9P
Percent Composition
C 56.74%, H 8.30%, N 11.34%, O 19.44%, P 4.18%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
94885-04-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
740.867
Exact Mass
740.424
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References

Schultz ML, Fawaz MV, Azaria RD, Hollon TC, Liu EA, Kunkel TJ, Halseth TA, Krus KL, Ming R, Morin EE, McLoughlin HS, Bushart DD, Paulson HL, Shakkottai VG, Orringer DA, Schwendeman AS, Lieberman AP. Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann-Pick diseases. BMC Med. 2019 Nov 11;17(1):200. doi: 10.1186/s12916-019-1423-5.

 PubMed ID: 31711490

Sengupta P, Seo AY, Pasolli HA, Song YE, Johnson MC, Lippincott-Schwartz J. A lipid-based partitioning mechanism for selective incorporation of proteins into membranes of HIV particles. Nat Cell Biol. 2019 Apr;21(4):452-461. doi: 10.1038/s41556-019-0300-y. Epub 2019 Apr 1.

 PubMed ID: 30936472

Ben-David O, Pewzner-Jung Y, Brenner O, Laviad EL, Kogot-Levin A, Weissberg I, Biton IE, Pienik R, Wang E, Kelly S, Alroy J, Raas-Rothschild A, Friedman A, Brügger B, Merrill AH Jr, Futerman AH. Encephalopathy caused by ablation of very long acyl chain ceramide synthesis may be largely due to reduced galactosylceramide levels. J Biol Chem. 2011 Aug 26;286(34):30022-33. doi: 10.1074/jbc.M111.261206. Epub 2011 Jun 24.

 PubMed ID: 21705317

McIntosh AL, Storey SM, Atshaves BP. Intracellular lipid droplets contain dynamic pools of sphingomyelin: ADRP binds phospholipids with high affinity. Lipids. 2010 Jun;45(6):465-77. doi: 10.1007/s11745-010-3424-1. Epub 2010 May 15.

 PubMed ID: 20473576
Certificates of Analysis

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