810130 | 16:0-06:0 NBD PC
1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
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16:0-06:0 NBD PC
1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine
16:0-06:0 NBD PC, also known as 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine, is a specialized phospholipid tagged with a nitrobenzoxadiazole (NBD) fluorophore, acting as a potential fluorescent probe or fluorescent analogue of phosphatidylcholine. Derivatives serve as fluorescent analogs of native lipids in various processes.
Applications
This fluorescent lipid is a crucial component for quantifying soluble and membrane-bound phospholipase A2 (PLA2) activity, as it provides precise and reliable results. It is extensively used in NBD-phospholipid translocation assays to study the movement of phospholipids across membranes, which is vital for understanding membrane dynamics.
Additionally, 16:0-06:0 NBD PC serves as an ideal molecular fluorescent marker to label lipids during friction tests. It enables detailed studies of lipid behavior under various conditions. It is also a helpful substrate for enzyme substrate specificity determination, enhancing our understanding of enzyme-lipid interactions. Furthermore, this versatile phospholipid facilitates studies in membrane biophysics and cell biology, making it essential for preparing small unilamellar vesicles.
Packaging
Avanti Research offers 16:0-06:0 NBD PC in powder and chloroform forms in 1 mg and 5 mg packaging to suit diverse research needs. The packaging is specially developed for optimal preservation.
Researchers choose 16:0-06:0 NBD PC from Avanti Research because of its high fluorescence intensity and stability, providing reliable and reproducible results.
CAS Registry Number is a Registered Trademark of the American Chemical Society
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- Certificate of Analysis (Lot No. 810130C-1MG-B-060 and 5324CGB060)
- Certificate of Analysis (Lot No. 810130P-5MG-C-061 and 5324PHC061)
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- Certificate of Analysis (Lot No. 810130P-5MG-A-062 and 5324PHA062)
- Certificate of Analysis (Lot No. 810130P-1MG-A-062 and 5324PGA062)
- Certificate of Analysis (Lot No. 810130P-5MG-B-062 and 5324PHB062)
- Certificate of Analysis (Lot No. 810130C-5MG-A-062 and 5324CHA062)
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