790310 | Transfection Reagent I
Transfection Reagent I, contains DOTAP:DOPE (1:1 w/w)
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Transfection Reagent I
Transfection Reagent I, contains DOTAP:DOPE (1:1 w/w)
DOTAP is one of the most widely used cationic lipids for gene transfection applications. DOTAP is proven to be efficient for in vitro and in vivo transfection applications. Various analogues of TAP are available for structure-activity relationship studies.
Simberg D, Weisman S, Talmon Y, Barenholz Y. DOTAP (and other cationic lipids): chemistry, biophysics, and transfection. Crit Rev Ther Drug Carrier Syst. 2004;21(4):257-317. doi: 10.1615/critrevtherdrugcarriersyst.v21.i4.10. PMID: 15638468.
Kim BK, Hwang GB, Seu YB, Choi JS, Jin KS, Doh KO. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes. Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001. doi: 10.1016/j.bbamem.2015.06.020. Epub 2015 Jun 23. PMID: 26112463.
PubMed ID: 26112463Pezzoli D, Kajaste-Rudnitski A, Chiesa R, Candiani G. Lipid-based nanoparticles as nonviral gene delivery vectors. Methods Mol Biol. 2013;1025:269-79. doi: 10.1007/978-1-62703-462-3_21. PMID: 23918345.
PubMed ID: 23918345Li Y, Bhindi R, Deng ZJ, Morton SW, Hammond PT, Khachigian LM. Inhibition of vein graft stenosis with a c-jun targeting DNAzyme in a cationic liposomal formulation containing 1,2-dioleoyl-3-trimethylammonium propane (DOTAP)/1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE). Int J Cardiol. 2013 Oct 9;168(4):3659-64. doi: 10.1016/j.ijcard.2013.05.092. Epub 2013 Jul 22. PMID: 23886527; PMCID: PMC3951723.
PubMed ID: 23886527- Certificate of Analysis (Lot No. 790310P-10MG-A-156 and 5242PIA156)
- Certificate of Analysis (Lot No. 790310P-200MG-A-157 and 5242PNA157)
- Certificate of Analysis (Lot No. 790310P-25MG-A-156 and 5242PJA156)
- Certificate of Analysis (Lot No. 790310P-500MG-A-157 and 5242PPA157)
- Certificate of Analysis (Lot No. 790310P-25MG-A-158 and 5242PJA158)
- Certificate of Analysis (Lot No. 790310P-200MG-A-158 and 5242PNA158)
- Certificate of Analysis (Lot No. 790310P-200MG-B-158 and 5242PNB158)
- Certificate of Analysis (Lot No. 790310P-200MG-A-159 and 5242PNA159)
- Certificate of Analysis (Lot No. 790310P-25MG-B-158 and 5242PJB158)