700086 | DHEA sulfate

Dehydroepiandrosterone sulfate (sodium salt)

DHEA sulfate

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50mg 700086P-50mg 700086P-50mg 1 x 50mg $664.00
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DHEA sulfate

Dehydroepiandrosterone sulfate (sodium salt)

DHEA sulfate is a metabolite of dehydroepiandrosterone (DHEA) produced by the addition of a sulfate group, catalyzed by the sulfotransferase enzymes SULT1A1 and SULT1E1, which also produce estrone sulfate from estrone. DHEA sulfate can also be back-converted to DHEA through the action of steroid sulfatase.

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C19H27NaO5S
Percent Composition
C 58.44%, H 6.97%, Na 5.89%, O 20.49%, S 8.21%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
651-48-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
390.469
Exact Mass
390.148
Synonyms
DHEA sulfate
DHEASDHEA-S
3β-hydroxy-5-androsten-17-one 3-sulfate (sodium salt)
5-androsten-3β-ol-17-one sulfate (sodium salt)
Prasterone sulfate (sodium salt)
References

Junker J, Chong I, Kamp F, Steiner H, Giera M, Müller C, Bracher F. Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol. Molecules. 2019 Jun 26;24(13). pii: E2353. doi: 10.3390/molecules24132353.

PubMed ID: 31247920

Chung KF, Qin N, Androutsellis-Theotokis A, Bornstein SR, Ehrhart-Bornstein M. Effects of dehydroepiandrosterone on proliferation and differentiation of chromaffin progenitor cells. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):141-8. doi: 10.1016/j.mce.2010.11.028. Epub 2010 Dec 2.

PubMed ID: 21130143

Dillon JS. Dehydroepiandrosterone, dehydroepiandrosterone sulfate and related steroids: their role in inflammatory, allergic and immunological disorders. Curr Drug Targets Inflamm Allergy. 2005 Jun;4(3):377-85.

PubMed ID: 16101547

Racchi M, Balduzzi C, Corsini E. Dehydroepiandrosterone (DHEA) and the aging brain: flipping a coin in the "fountain of youth". CNS Drug Rev. 2003 Spring;9(1):21-40.

PubMed ID: 12595910

Ebeling P, Koivisto VA. Physiological importance of dehydroepiandrosterone. Lancet. 1994 Jun 11;343(8911):1479-81.

PubMed ID: 7911183
Certificates of Analysis

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