700060 | desmosterol

3ß-hydroxy-5,24-cholestadiene

desmosterol

Powder

Size SKU Packaging Price
5mg 700060P-5mg 700060P-5mg 1 x 5mg $243.95
10mg 700060P-10mg 700060P-10mg 1 x 10mg $382.00
Request Bulk Pricing

Info

desmosterol

3ß-hydroxy-5,24-cholestadiene

Desmosterol is a precursor to cholesterol. Desmosterol has some potential uses in pharmaceuticals due to its abilities for treating inflammatory and neurodegenerative disorders.
Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H44O
Percent Composition
C 84.31%, H 11.53%, O 4.16%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
313-04-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
384.638
Exact Mass
384.339
Synonyms
24-dehydrocholesterol
5,24-cholestadien-3ß-ol
110798
Solubility in Different Solvents
Soluble in DMSO at 0.1mg/mL, soluble in ethanol and Hexane:Ethyl Acetate (7:3) at 5mg/mL
References

Carro MLM, Peñalva DA, Antollini SS, Hozbor FA, Buschiazzo J. Cholesterol and desmosterol incorporation into ram sperm membrane before cryopreservation: Effects on membrane biophysical properties and sperm quality. Biochim Biophys Acta Biomembr. 2020 Sep 1;1862(9):183357. doi: 10.1016/j.bbamem.2020.183357. Epub 2020 May 13. PMID: 32416195.

PubMed ID: 32416195

Miyazaki T, Sasaki SI, Toyoda A, Wei FY, Shirai M, Morishita Y, Ikegami T, Tomizawa K, Honda A. Impaired bile acid metabolism with defectives of mitochondrial-tRNA taurine modification and bile acid taurine conjugation in the taurine depleted cats. Sci Rep. 2020 Mar 18;10(1):4915. doi: 10.1038/s41598-020-61821-6. PMID: 32188916; PMCID: PMC7080809.

PubMed ID: 32188916

Webb LM, Sengupta S, Edell C, Piedra-Quintero ZL, Amici SA, Miranda JN, Bevins M, Kennemer A, Laliotis G, Tsichlis PN, Guerau-de-Arellano M. Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity. J Clin Invest. 2020 Feb 24:131254. doi: 10.1172/JCI131254. Epub ahead of print. PMID: 32091410.

PubMed ID: 32091410

Webb LM, Sengupta S, Edell C, Piedra-Quintero ZL, Amici SA, Miranda JN, Bevins M, Kennemer A, Laliotis G, Tsichlis PN, Guerau-de-Arellano M. Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity. J Clin Invest. 2020 Feb 24:131254. doi: 10.1172/JCI131254. Epub ahead of print. PMID: 32091410.

PubMed ID: 32091410

Li G, Wang Q, Kakuda S, London E. Nanodomains can persist at physiologic temperature in plasma membrane vesicles and be modulated by altering cell lipids. J Lipid Res. 2020 Jan 21:jlr.RA119000565. doi: 10.1194/jlr.RA119000565. Epub ahead of print. PMID: 31964764.

PubMed ID: 31964764

Chakrabarti P, Morré JT, Lucas HM, Maier CS, Sagili RR. The omics approach to bee nutritional landscape. Metabolomics. 2019 Sep 20;15(10):127. doi: 10.1007/s11306-019-1590-6.

PubMed ID: 31538263
Certificates of Analysis

Related Products

700188
14-dehydro zymostenol 14-dehydro zymostenol Buy Now
700099
lanosterol-95 lanosterol-95 Buy Now
810253
dehydroergosterol (DHE) dehydroergosterol (DHE) Buy Now
700114
5α-7,24-cholestadiene 5α-7,24-cholestadiene Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }

Change Custom Packaging
${ item.salePriceAsCurrency }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.type }: ${ adjustment.name } ${ adjustment.amountAsCurrency }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }

Have a promo code? Enter it in your cart to apply your discount and enjoy the savings on your purchase! Finalize Cart