700053 | 25-hydroxycholesterol-d6

cholest-5-ene-3ß,25-diol-d6

25-hydroxycholesterol-d6

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1mg 700053P-1mg 700053P-1mg 1 x 1mg $358.63
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Info

25-hydroxycholesterol-d6

cholest-5-ene-3ß,25-diol-d6

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C27H40D6O2
Percent Composition
C 79.35%, H 12.82%, O 7.83%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
88247-69-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
408.69
Exact Mass
408.387
Synonyms
26,26,26,27,27,27-hexadeuterocholest-5-ene-3ß,25-diol
25-hydroxycholest-5-en-3-ol(d6)
References

Ménégaut L, Thomas C, Jalil A, Julla JB, Magnani C, Ceroi A, Basmaciyan L, Dumont A, Le Goff W, Mathew MJ, Rébé C, Dérangère V, Laubriet A, Crespy V, Pais de Barros JP, Steinmetz E, Venteclef N, Saas P, Lagrost L, Masson D. Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages. Cell Rep. 2020 May 19;31(7):107665. doi: 10.1016/j.celrep.2020.107665. PMID: 32433974.

PubMed ID: 32433974

Anosov AA, Smirnova EY, Sharakshane AA, Nikolayeva EA, Zhdankina YS. Increase in the current variance in bilayer lipid membranes near phase transition as a result of the occurrence of hydrophobic defects. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183147. doi: 10.1016/j.bbamem.2019.183147. Epub 2019 Dec 6. PMID: 31812627.

PubMed ID: 31874216

Rossin D, Dias IHK, Solej M, Milic I, Pitt AR, Iaia N, Scoppapietra L, Devitt A, Nano M, Degiuli M, Volante M, Caccia C, Leoni V, Griffiths HR, Spickett CM, Poli G, Biasi F. Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration. Free Radic Biol Med. 2019 Mar 23;136:35-44. doi: 10.1016/j.freeradbiomed.2019.03.020. [Epub ahead of print]

PubMed ID: 30910555

Solheim S, Hutchinson SA, Lundanes E, Wilson SR, Thorne JL, Roberg-Larsen H. Fast liquid chromatography-mass spectrometry reveals side chain oxysterol heterogeneity in breast cancer tumour samples. J Steroid Biochem Mol Biol. 2019 Feb 16. pii: S0960-0760(18)30754-4. doi: 10.1016/j.jsbmb.2019.02.004. [Epub ahead of print]

PubMed ID: 30779932

Becares N, Gage MC, Voisin M, Shrestha E, Martin-Gutierrez L, Liang N, Louie R, Pourcet B, Pello OM, Luong TV, Goñi S, Pichardo-Almarza C, Røberg-Larsen H, Diaz-Zuccarini V, Steffensen KR, O'Brien A, Garabedian MJ, Rombouts K, Treuter E, Pineda-Torra I. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. Cell Rep. 2019 Jan 22;26(4):984-995.e6. doi: 10.1016/j.celrep.2018.12.094.

PubMed ID: 30673619
Certificates of Analysis

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