700021 | 27-hydroxycholesterol
cholest-(25R)-5-ene-3ß,27-diol
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27-hydroxycholesterol
cholest-(25R)-5-ene-3ß,27-diol
CAS Registry Number is a Registered Trademark of the American Chemical Society
110818
Powered by BiozOlżyńska A, Kulig W, Mikkolainen H, Czerniak T, Jurkiewicz P, Cwiklik L, Rog T, Hof M, Jungwirth P, Vattulainen I. Tail-Oxidized Cholesterol Enhances Membrane Permeability for Small Solutes. Langmuir. 2020 Aug 28. doi: 10.1021/acs.langmuir.0c01590. Epub ahead of print. PMID: 32804507.
PubMed ID: 32804507Germano A, Rossin D, Leoni V, Iaia N, Saba L, Basile V, Puglisi S, Caccia C, Poli G, Biasi F, Terzolo M. Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma. Cells. 2020 Apr 4;9(4):885. doi: 10.3390/cells9040885. PMID: 32260362; PMCID: PMC7226725.
PubMed ID: 32260362Abrams ME, Johnson KA, Perelman SS, Zhang LS, Endapally S, Mar KB, Thompson BM, McDonald JG, Schoggins JW, Radhakrishnan A, Alto NM. Oxysterols provide innate immunity to bacterial infection by mobilizing cell surface accessible cholesterol. Nat Microbiol. 2020 Apr 13. doi: 10.1038/s41564-020-0701-5. Epub ahead of print. PMID: 32284563.
PubMed ID: 32284563Xiao L, Luo G, Guo X, Jiang C, Zeng H, Zhou F, Li Y, Yu J, Yao P. Macrophage iron retention aggravates atherosclerosis: Evidence for the role of autocrine formation of hepcidin in plaque macrophages. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct 27:158531. doi: 10.1016/j.bbalip.2019.158531. [Epub ahead of print]
PubMed ID: 31666189Stottrup BL, TigreLazo J, Bagonza VB, Kunz JC, Zasadzinski JA. Comparison of Line Tension Measurement Methods for Lipid Monolayers at Liquid-Liquid Coexistence. Langmuir. 2019 Aug 7. doi: 10.1021/acs.langmuir.9b01696. [Epub ahead of print]
PubMed ID: 31343892Hutchinson SA, Lianto P, Moore JB, Hughes TA, Thorne JL. Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells. Int J Mol Sci. 2019 Jul 2;20(13). pii: E3241. doi: 10.3390/ijms20133241.
PubMed ID: 31269628Kunz S, Matysik S. A comprehensive method to determine sterol species in human faeces by GC-triple quadrupole MS. J Steroid Biochem Mol Biol. 2019 Mar 25;190:99-103. doi: 10.1016/j.jsbmb.2019.03.014. [Epub ahead of print]
PubMed ID: 30923016Wang X, Sun J, Zhao XE, Xu Y, Sun L, Zhu S, You J, Wang X. Stable isotope labeling derivatization coupled with magnetic dispersive solid phase extraction for the determination of hydroxyl-containing cholesterol and metabolites by in vivo microdialysis and ultra-high performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2019 Feb 14. pii: S0021-9673(19)30151-7. doi: 10.1016/j.chroma.2019.02.021. [Epub ahead of print]
PubMed ID: 30797576Solheim S, Hutchinson SA, Lundanes E, Wilson SR, Thorne JL, Roberg-Larsen H. Fast liquid chromatography-mass spectrometry reveals side chain oxysterol heterogeneity in breast cancer tumour samples. J Steroid Biochem Mol Biol. 2019 Feb 16. pii: S0960-0760(18)30754-4. doi: 10.1016/j.jsbmb.2019.02.004. [Epub ahead of print]
PubMed ID: 30779932Kim, S.M., B.Y. Kim, S.A. Lee, S.K. Eo, Y. Yun, C.D. Kim, and K. Kim. (2014). 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes. Toxicol Appl Pharmacol 274:462-70. [PubMed]
PubMed ID: 24370436Nunes, V.S., N.B. Panzoldo, C.C. Leanca, E.S. Parra, V.S. Zago, E.J. da Silva, P.M. Cazita, E.R. Nakandakare, E.C. de Faria, and E.C. Quintao. (2014). Increased 27-hydroxycholesterol plasma level in men with low high density lipoprotein-cholesterol may circumvent their reduced cell cholesterol efflux rate. Clin Chim Acta 433:169-73. [PubMed]
PubMed ID: 24657483Gamba, P., M. Guglielmotto, G. Testa, D. Monteleone, C. Zerbinati, S. Gargiulo, F. Biasi, L. Iuliano, G. Giaccone, A. Mauro, G. Poli, E. Tamagno, and G. Leonarduzzi. (2014). Up-regulation of beta-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine. Aging Cell 13:561-72. [PubMed]
PubMed ID: 24612036Kim, S.M., H. Jang, Y. Son, S.A. Lee, S.S. Bae, Y.C. Park, S.K. Eo, and K. Kim. (2013). 27-hydroxycholesterol induces production of tumor necrosis factor-alpha from macrophages. Biochem Biophys Res Commun 430:454-9. [PubMed]
PubMed ID: 23246833Nelson, E.R., S.E. Wardell, J.S. Jasper, S. Park, S. Suchindran, M.K. Howe, N.J. Carver, R.V. Pillai, P.M. Sullivan, V. Sondhi, M. Umetani, J. Geradts, and D.P. McDonnell. (2013). 27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology. Science 342:1094-8. [PubMed]
PubMed ID: 24288332Wu, Q., T. Ishikawa, R. Sirianni, H. Tang, J.G. McDonald, I.S. Yuhanna, B. Thompson, L. Girard, C. Mineo, R.A. Brekken, M. Umetani, D.M. Euhus, Y. Xie, and P.W. Shaul. (2013). 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth. Cell Rep 5:637-45. [PubMed]
PubMed ID: 24210818Rossouw, J.E., R.L. Prentice, J.E. Manson, A.K. Aragaki, J. Hsia, L.W. Martin, L. Kuller, K.C. Johnson, C. Eaton, R. Jackson, M. Trevisan, M. Allison, and R.C. Hoogeveen. (2012). Relationships of coronary heart disease with 27-hydroxycholesterol, low-density lipoprotein cholesterol, and menopausal hormone therapy. Circulation 126:1577-86. [PubMed]
PubMed ID: 22932256Shafaati, M., A. Marutle, H. Pettersson, A. Lovgren-Sandblom, M. Olin, I. Pikuleva, B. Winblad, A. Nordberg, and I. Bjorkhem. (2011). Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutation. J Lipid Res 52:1004-10. [PubMed]
PubMed ID: 21335619Karuna, R., A.G. Holleboom, M.M. Motazacker, J.A. Kuivenhoven, R. Frikke-Schmidt, A. Tybjaerg-Hansen, S. Georgopoulos, M. van Eck, T.J. van Berkel, A. von Eckardstein, and K.M. Rentsch. (2011). Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism. Atherosclerosis 214:448-55. [PubMed]
PubMed ID: 21130455Heverin, M., S. Meaney, D. Lutjohann, U. Diczfalusy, J. Wahren, and I. Bjorkhem. (2005). Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain. J Lipid Res 46:1047-52. [PubMed]
PubMed ID: 15741649- Certificate of Analysis (Lot No. 700021P-1MG-A-014 and 5107PGA014)
- Certificate of Analysis (Lot No. 700021P-25MG-A-014 and 5107PJA014)
- Certificate of Analysis (Lot No. 700021P-5MG-A-014 and 5107PHA014)
- Certificate of Analysis (Lot No. 700021P-1MG-B-014 and 5107PGB014)
- Certificate of Analysis (Lot No. 700021P-1MG-D-014 and 5107PGD014)
- Certificate of Analysis (Lot No. 700021P-25MG-B-014 and 5107PJB014)
- Certificate of Analysis (Lot No. 700021P-5MG-C-014 and 5107PHC014)
- Certificate of Analysis (Lot No. 700021P-1MG-E-014 and 5107PGE014)
- Certificate of Analysis (Lot No. 700021P-1MG-F-014 and 5107PGF014)
- Certificate of Analysis (Lot No. 700021P-5MG-B-014 and 5107PHB014)
- Certificate of Analysis (Lot No. 700021P-5MG-A-015 and 5107PHA015)
- Certificate of Analysis (Lot No. 700021P-1MG-A-015 and 5107PGA015)
- Certificate of Analysis (Lot No. 700021P-5MG-B-015 and 5107PHB015)
- Certificate of Analysis (Lot No. 700021P-5MG-C-015 and 5107PHC015)
- Certificate of Analysis (Lot No. 700021P-1MG-C-015 and 5107PGC015)
