Section Menu

699857 | FP-20, sodium salt

sodium (2R,3S,4R,5R,6S)-5-dodecanamido-4,6-bis(dodecanoyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl phosphate

FP-20, sodium salt

Powder

Size SKU Packaging Price
5mg 699857P-5mg 699857P-5mg 1 x 5mg $377.35
10mg 699857P-10mg 699857P-10mg 1 x 10mg $603.70
Request Bulk Pricing
Info

FP-20, sodium salt

sodium (2R,3S,4R,5R,6S)-5-dodecanamido-4,6-bis(dodecanoyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl phosphate

Sodium (2R,3S,4R,5R,6S)-5-dodecanamido-4,6-bis(dodecanoyloxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl phosphate, or FP-20, sodium salt is a synthetic adjuvant and toll-like receptor 4 (TLR4) agonist designed to improve immune responses in vaccine formulations. It features a glucosamine monosaccharide core with three C12 fatty acid chains and a phosphate group. 

FP-20, sodium salt is engineered to stimulate innate immunity that leads to robust adaptive immune activation. FP-20’s potent immunostimulatory properties make it a promising candidate for next-generation vaccine adjuvant systems.

Application

Research involving FP-20 shows potential for increasing vaccine efficacy by improving cancer immunotherapy and improving the immune system’s response to tumor-associated antigens.

Additionally, researchers are exploring FP-20’s role in vaccines that target infectious diseases, including the flu, HIV, and tuberculosis. Its powerful ability to trigger strong immune responses shows potential for improving vaccine effectiveness across various pathogens.

Another notable characteristic of FP-20 is its ability to be used alongside other adjuvants, such as QS-21, to create immune-enhancing effects and boost vaccine performance further.

Packaging

Avanti Research™ provides FP-20, sodium salt in powder (5mg and 10mg) for targeted research in cancer, infectious diseases, and more.

Our 50+ years of experience are here to put your research a step ahead. 

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula

C42H79NNaO11P

Percent Composition

C 60.92%, H 9.25%, H 1.69%, Na 2.78%, O 21.25%, P 3.74%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
3056013-47-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
828.05
Exact Mass
827.53
Downloads
References

J. Med. Chem. 2023, 66, 4, 3010–3029Publication Date:February 2, 2023https://doi.org/10.1021/acs.jmedchem.2c01998

ACS Omega 2023, 8, 39, 36412–36417Publication Date:September 18, 2023https://doi.org/10.1021/acsomega.3c05363

J. Med. Chem. 2021, 64, 16, 12261–12272Publication Date:August 12, 2021https://doi.org/10.1021/acs.jmedchem.1c00896

Recommended Products

699856
FP-18, sodium salt FP-18, sodium salt Buy Now
860782
α-Glucosyl FP20 α-Glucosyl FP20 Buy Now
860780
α-Galactosyl FP20 α-Galactosyl FP20 Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }
Change Custom Packaging 		$ ${ item.total.toFixed(2) }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }
Finalize Cart