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250520 | N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

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1g 250520P-1g 250520P-1g 1 x 1g $107.44
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N-DODECYL-ß-D-MALTOSIDE (DDM, 85%)

This product is a more cost-effective alternative to Avandecrys DDM that can be used for membrane protein extraction and purification.
DDM is the most widely used detergent for the isolation and purification of GPCR’s.
In addition, LacY likely favors a higher-energy intermediate periplasmic-open conformation in situ, but collapses to a lower-energy periplasmic-closed conformation in DDM after purification. It is interesting to note that the branched-chain maltoside detergents stabilize LacY in the membrane-embedded form (see Related Products).

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C24H46O11
Percent Composition
C 56.45%, H 9.08%, O 34.47%
Purity
>85%; contains <15% alpha isomer
Stability
1 Year
Storage Temperature
-20°C
CAS Number
69227-93-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
510.615
Exact Mass
510.304
Synonyms
DDM
lauryl maltoside dodecyl
4-O-α-D-glucopyranosyl-β-D-glucopyranoside
CMC
~0.2 mM
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References

Bruggisser J, Tarek B, Wyder M, Müller P, von Ballmoos C, Witz G, Enzmann G, Deutsch U, Engelhardt B, Posthaus H. CD31 (PECAM-1) Serves as the Endothelial Cell-Specific Receptor of Clostridium perfringens β-Toxin. Cell Host Microbe. 2020 Jul 8;28(1):69-78.e6. doi: 10.1016/j.chom.2020.05.003. Epub 2020 Jun 3. PMID: 32497498.

 PubMed ID: 32497498
Certificates of Analysis

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