Globosides

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      860128 - C18:0-d7 GB4 Ceramide (d18:1/18:0-d7), synthetic
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      860147 - C18:0 GB3 Ceramide (d18:1/18:0)
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      860150 - C18:0 GB4 Ceramide (d18:1/18:0), synthetic
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      860166 - C24:1 GB4 Ceramide (d18:1/24:1), synthetic
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      860167 - C24:1 GB3 Ceramide (d18:1/24:1), synthetic
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      860168 - C24:1 GM3 Ceramide (d18:1/24:1), synthetic
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      860682 - Lyso GB3-d7 (synthetic)
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      860699 - C17:0 GB3 (synthetic)
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      860701 - C17:0 Gb2
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      860720 - Lyso iGB3 (synthetic)
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      860721 - Lyso iGB3-d7 (synthetic)
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      860722 - C17:0 iGB3 (synthetic)
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      860952 - Lyso GB3 (synthetic)
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      860953 - Lyso Gb2

Globosides: Precision and purity for advanced research applications

Globosides are a subclass of glycosphingolipids that feature a ceramide backbone linked to multiple sugar residues, primarily glucose and galactose. These neutral glycolipids play a pivotal role in cell recognition, adhesion, and signal transduction, making them essential for studying cell membrane dynamics, pathogen interactions, and immunological responses. Avanti Research offers a diverse portfolio of high-purity globosides, synthesized under stringent quality control to ensure batch-to-batch consistency for reliable results in complex research applications.

Our globosides are ideal for:

  • Lipidomics and glycomics research: Analyze the intricate glycosphingolipid profiles in various biological systems with confidence.
  • Pathogen-host interaction studies: Explore how pathogens recognize and bind to globoside receptors during infection.
  • Cell adhesion and signal transduction investigations: Uncover the mechanisms behind cell-cell communication and immune responses.

Why choose Avanti Research’s globosides?
Our expertise in lipid synthesis ensures unmatched purity and reproducibility, which is critical when working with complex glycosphingolipids. Our globosides undergo rigorous quality assurance testing, ensuring they meet the highest standards required for lipidomics, structural analysis, and functional assays.

Explore Avanti Research’s globoside portfolio today!
Bring greater precision and consistency to your lipid research with Avanti’s high-quality globoside offerings.

References:
  1. Hakomori, S. (2002). Glycosphingolipids in cellular interaction, differentiation, and oncogenesis. Annual Review of Biochemistry, 71(1), 491–537.
  2. Lingwood, C. A., & Binnington, B. (2014). Glycosphingolipids in host-pathogen interactions. Biochemical Society Transactions, 42(3), 559–563.
  3. Schnaar, R. L., & Kinoshita, T. (2015). Glycosphingolipids. Essentials of Glycobiology, 3rd ed. Cold Spring Harbor Laboratory Press.